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Results 1 to 25 of 1286

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Enhancement of Radiation-induced DNA Damage and Inhibition of Its Repair by a Novel Camptothecin AnalogGE HUANG; HUIJUAN WANG; YANG, Li-Xi et al.Anticancer research. 2010, Vol 30, Num 3, pp 937-944, issn 0250-7005, 8 p.Article

Validation study of a method for assaying DE-310, a macromolecular carrier conjugate containing an anti-tumor camptothecin derivative, and the free drug in human plasma by HPLC and LC/MS/MSOGUMA, Toshihiro; CICCI, Dino; GAUDETTE, Fleur et al.Journal of chromatography. B. 2005, Vol 818, Num 2, pp 249-256, issn 1570-0232, 8 p.Article

A TOTAL SYNTHESIS OF CAMPTOTHECIN AND DEETHYLDEOXYCAMPTOTHECINMEYERS AI; NOLEN RL; COLLINGTON EW et al.1973; J. ORG. CHEM.; U.S.A.; DA. 1973; VOL. 38; NO 11; PP. 1974-1982; BIBL. 28 REF.Serial Issue

REAKTIONEN AN INDOLDERIVATEN. XXVIII. ALKYLIERUNG VON CAMPTOTHECIN-VORSTUFEN - EIN NEUER WEG ZUM CAMPTOTHECIN = REACTIONS DES DERIVES DE L'INDOLE. XXVIII. ALKYLATION D'INTERMEDIAIRES DE CAMPTOTHECINE, UNE NOUVELLE VOIE D'ACCES A LA CAMPTOTHECINEKROHN K; WINTERFELDT E.1975; CHEM. BER.; DTSCH.; DA. 1975; VOL. 108; NO 9; PP. 3030-3042; ABS. ANGL.; BIBL. 11 REF.Article

Renal Function as a Predictor of Irinotecan-induced NeutropeniaDE JONG, F. A; VAN DER BOL, J. M; MATHIJSSEN, R. H. J et al.Clinical pharmacology and therapeutics. 2008, Vol 84, Num 2, pp 254-262, issn 0009-9236, 9 p.Article

Clinical Determinants of Response to Irinotecan-Based Therapy Derived from Cell Line ModelsALLEN, Wendy L; COYLE, Vicky M; JOHNSTON, Patrick G et al.Clinical cancer research (Print). 2008, Vol 14, Num 20, pp 6647-6655, issn 1078-0432, 9 p.Article

Irinotecan Pharmacogenetics : Influence of Pharmacodynamic GenesHOSKINS, Janelle M; MARCUELLO, Eugenio; ALTES, Albert et al.Clinical cancer research. 2008, Vol 14, Num 6, pp 1788-1796, issn 1078-0432, 9 p.Article

Transport characteristics of 9-nitrocamptothecin in the human intestinal cell line Caco-2 and everted gut sacsXIANYI SHA; XIAOLING FANG.International journal of pharmaceutics. 2004, Vol 272, Num 1-2, pp 161-171, issn 0378-5173, 11 p.Article

A Novel Camptothecin Derivative Incorporated in Nano-Carrier Induced Distinguished Improvement in Solubility, Stability and Anti-tumor Activity Both In Vitro and In VivoMIN HAN; HE, Cai-Xia; GAO, Jian-Qing et al.Pharmaceutical research. 2009, Vol 26, Num 4, pp 926-935, issn 0724-8741, 10 p.Article

Irinotecan Use During PregnancyTAYLOR, Justin; AMANZE, Adanna; DI FEDERICO, Elaine et al.Obstetrics and gynecology (New York. 1953). 2009, Vol 114, Num 2, pp 451-452, issn 0029-7844, 2 p., 2Article

The effect of 10-hydroxycamptothecine in preventing fibroblast proliferation and epidural scar adhesion after laminectomy in ratsYU SUN; LEI WANG; SIXIN SUN et al.European journal of pharmacology. 2008, Vol 593, Num 1-3, pp 44-48, issn 0014-2999, 5 p.Article

MEN4901/T-0128, a new camptothecin derivative-carboxymethyldextran conjugate, has potent antitumor activities in a panel of human tumor xenografts in nude miceFUJITA, Fumiko; KOIKE, Masako; KUDOH, Shinzoh et al.Clinical cancer research. 2005, Vol 11, Num 4, pp 1650-1657, issn 1078-0432, 8 p.Article

Potent and sustained inhibition of HIF-1α and downstream genes by a polyethyleneglycol-SN38 conjugate, EZN-2208, results in anti-angiogenic effectsSAPRA, Puja; KRAFT, Patricia; PASTORINO, Fabio et al.Angiogenesis (London). 2011, Vol 14, Num 3, pp 245-253, issn 0969-6970, 9 p.Article

A novel method to load topotecan into liposomes driven by a transmembrane NH4EDTA gradientYUEHUI YANG; YANLING MA; SHAONING WANG et al.European journal of pharmaceutics and biopharmaceutics. 2012, Vol 80, Num 2, pp 332-339, issn 0939-6411, 8 p.Article

Pharmacogenetic Pathway Analysis of IrinotecanROSNER, G. L; PANETTA, J. C; INNOCENTI, F et al.Clinical pharmacology and therapeutics. 2008, Vol 84, Num 3, pp 393-402, issn 0009-9236, 10 p.Article

Targeting atypical trypanosomatid DNA topoisomerase IBALANA-FOUCE, Rafael; REDONDO, Carmen M; PEREZ-PERTEJO, Yolanda et al.Drug discovery today. 2006, Vol 11, Num 15, pp 733-740, issn 1359-6446, 8 p.Article

Validation study of assay method for DE-310, a novel polymer-bound camptothecin derivative, and the free drug in mouse plasma by liquid chromatography with fluorimetric detectionOGUMA, Toshihiro; KONNO, Tomomi; NAKAOKA, Minoru et al.Journal of chromatography. B. 2004, Vol 801, Num 2, pp 157-164, issn 1570-0232, 8 p.Article

Design and one-pot synthesis of new 7-acyl camptothecin derivatives as potent cytotoxic agentsLIU, Ying-Qian; WEI DAI; WANG, Chih-Ya et al.Bioorganic & medicinal chemistry letters (Print). 2012, Vol 22, Num 24, pp 7659-7661, issn 0960-894X, 3 p.Article

Comprehensive Pharmacogenetic Analysis of Irinotecan Neutropenia and PharmacokineticsINNOCENTI, Federico; KROETZ, Deanna L; SCHUETZ, Erin et al.Journal of clinical oncology. 2009, Vol 27, Num 16, pp 2604-2614, issn 0732-183X, 11 p.Article

Irinotecan Side Effects Relieved by the Use of HI-6 Oxime: In Vivo Experimental ApproachLUCIC VRDOLJAK, Ana; BEREND, Suzana; ZELJEZIC, Davor et al.Basic & clinical pharmacology & toxicology (Print). 2009, Vol 105, Num 6, pp 401-409, issn 1742-7835, 9 p.Article

Antitumour drugs impede DNA uncoiling by topoisomerase IKOSTER, Daniel A; PALLE, Komaraiah; BOT, Elisa S. M et al.Nature (London). 2007, Vol 448, Num 7150, pp 213-217, issn 0028-0836, 5 p.Article

Semi-synthesis and biological activity of γ-lactones analogs of camptothecinMINGZONG LI; WEIDONG TANG; FUXING ZENG et al.Bioorganic & medicinal chemistry letters (Print). 2008, Vol 18, Num 24, pp 6441-6443, issn 0960-894X, 3 p.Article

Safety pharmacology of CKD-602, a novel anticancer agentEUN JOO KIM; RAE KYONG LEE; JEONG EUN SUH et al.Arzneimittel-Forschung. 2003, Vol 53, Num 4, pp 272-279, issn 0004-4172, 8 p.Article

EXPERIMENTS ON THE SYNTHESIS OF DL-CAMPTOTHECIN. IV. SYNTHESIS AND ANTILEUKEMIC ACTIVITY OF DL-CAMPTOTHECIN ANALOGUESSUGASAWA T; TOYODA T; UCHIDA N et al.1976; J. MEDICIN. CHEM.; U.S.A.; DA. 1976; VOL. 19; NO 5; PP. 675-679; BIBL. 5 REF.Article

DIE CAMPTOTHECIN-OXIDATION = OXYDATION DE LA CAMPTOTHECINEKROHN K; OHLENDORF HW; WINTERFELDT E et al.1976; CHEM. BER.; DTSCH.; DA. 1976; VOL. 109; NO 4; PP. 1389-1394; ABS. ANGL.; BIBL. 7 REF.Article

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